Reduce Knee Pain and Avoid Joint Replacement Surgery

Are you struggling with chronic knee pain from osteoarthritis? You may worry that knee replacement surgery is your only option, but there are newer treatments that can provide relief with less discomfort, scarring and downtime. At Minimally Invasive Medical Group, we use genicular artery embolization (GAE) to reduce knee pain and help you avoid joint replacement surgery.

What Is Genicular Artery Embolization?

Osteoarthritis is a frequent cause of knee pain, especially in later life. After decades of motion, natural wear and tear reduces the protective cartilage that covers your bones and cushions the joint.


Without protection, the bone ends catch and rub, creating inflammation. The inflammation causes long-term joint pain that steadily gets worse. The knee joint becomes stiffer and weaker as the condition progresses, and you may eventually lose mobility and function.

Genicular artery embolization blocks some of the blood vessels that contribute to these problems. Reducing blood flow into the joint helps decrease inflammation and pain, giving you relief from discomfort without the need to remove or replace any part of your knee.


GAE is safe and effective, lasts for years and is covered by medical insurance. You can even have the procedure after knee replacement surgery if you still experience pain.

How Does GAE Work?

Don't settle for less. Get the body you want.

During a GAE procedure, the interventional radiologist punctures the skin to access the artery, guiding a catheter to the genicular arteries using X-ray imaging. They release microspheres that block blood flow to the inflamed areas of the knee, reducing inflammation while preserving healthy circulation to the rest of the joint.

Before recommending a treatment plan, our expert team evaluates each patient’s symptoms, medical history, and goals. GAE can effectively reduce knee pain for many with osteoarthritis, but we start with a consultation to determine if it’s the right choice for you.


GAE is versatile and has no strict age or weight limitations, making it suitable for those who have had knee surgery but still experience pain, as well as patients looking to preserve the option of future knee replacement.

You may be a good candidate for genicular artery embolization if you:

  • Experience chronic knee pain from osteoarthritis that affects your daily activities
  • Have not found adequate relief from conservative treatments like medications or physical therapy
  • Have tried steroid injections but found the relief 
  • too temporary
  • Do not wish to use medications long-term
  • Want to avoid or delay knee replacement surgery
  • Are not a good candidate for knee replacement
  • Desire a solution with minimal downtime

Benefits of Genicular Artery Embolization

Knee osteoarthritis is a progressive condition that becomes increasingly painful. Knee replacement is often the suggested solution, but you may not be a good candidate for surgery, or you may simply not be interested in an invasive procedure.


GAE is an alternative option for reducing knee pain with many additional benefits:

  • Minimally invasive, outpatient procedure
  • No large incisions
  • No removal of bone
  • No general anesthesia
  • No overnight hospital stay
  • Minimal downtime
  • Targeted treatment that only affects the problematic area
  • Lower risk of complications compared to invasive surgery
  • No age, weight or health condition restrictions
  • Preserves your natural knee joint
  • No effect on candidacy for future knee replacement
  • Long-lasting pain relief that can extend for months or years
  • Covered by Medicare

What to Expect During Treatment

Genicular Artery Embolization Recovery

The OCIR team ensures a comfortable experience during the GAE procedure, which lasts 60-90 minutes. On the procedure day, patients arrive at a modern outpatient facility, where an IV line is placed for moderate sedation and medications. The treatment area in the upper thigh is cleaned and numbed. Patients lie on their backs while an interventional radiologist uses advanced imaging to target problematic vessels in the knee. Patients remain awake, feeling relaxed and only slight pressure. After the procedure, patients recover until it’s safe to discharge, with the team monitoring vitals and the procedure site.

Most patients go home a few hours after the procedure with a small bandage on the upper thigh; no stitches are needed. Mild soreness at the site may last one to two days.


Our team will provide care instructions for the access site and recovery guidelines. Many patients return to desk work in one to two days and light activities within a week. We'll determine the timeline for returning to strenuous activities based on your healing.


You might notice some improvement in knee pain immediately, with more significant relief expected after two weeks and continued improvement after one month.

Real Patients with Real Stories

"About as smooth and comfortable of an experience as I could have hoped for dealing with an uncomfortable condition. I would recommend Dr. Syn and this office without hesitation."


- Adam F.

"Dr Syn was fantastic. He was patient, explained everything, in no rush to get to the next person. The staff is wonderful. Nobody wants to go the doctor, but they make it as great of an experience as possible, especially considering the sensitive of the issues. Highly recommend Dr Syn."

- Brad R.

"Dr. Syn has been amazing. He has thoroughly explained the process allowing me to make an informed decision. I went through 6 months of excruciating pain daily prior to my surgery and it all went away 3 days after surgery. Posting this one month post op and I feel great. I would highly recommend Dr. Syn."

- Clint S.

Got Questions?We Have Answers

How effective is GAE for knee pain?

Clinical studies show that GAE provides significant pain relief for approximately 75-85% of patients with knee osteoarthritis. Most patients experience a meaningful reduction in pain levels within four to six weeks, with continued improvement over several months. The procedure has shown particular success in patients with moderate to severe knee pain who haven’t responded well to conservative treatments. Many patients report being able to return to activities they had previously given up due to pain.

How long do the results from GAE last?

The pain relief from GAE can last several years for many patients. Studies tracking patients for up to five years show sustained improvement in pain and function. Unlike steroid injections that typically provide relief for 3-6 months, GAE addresses the underlying cause of inflammation, leading to longer-lasting results. Some patients may experience a gradual return of symptoms over time as osteoarthritis progresses, but the procedure can be safely repeated if needed.

Can I have GAE if I've already had knee replacement surgery?

Absolutely. GAE can be performed even after knee replacement surgery if you’re still experiencing pain. Sometimes, patients continue to have discomfort following joint replacement due to ongoing inflammation in the surrounding tissues. GAE can effectively target these areas without affecting the artificial joint components. This makes it an excellent option for managing post-surgical pain that hasn’t responded to other treatments.

How soon can I return to normal activities after GAE?

Most patients can return to desk work and light activities within one to two days. You’ll need to avoid heavy lifting or strenuous exercise for about a week to allow the access site to heal. Walking is encouraged the day after treatment to promote healthy circulation. Many patients find they can gradually return to activities like golf, gardening or hiking within two to four weeks.

Will I need physical therapy after GAE?

While physical therapy isn’t always required after GAE, many patients benefit from a structured rehabilitation program. As your pain decreases, physical therapy can help restore strength and mobility that may have been lost due to prolonged inactivity. We often recommend waiting four to six weeks after the procedure before starting to allow the full benefits of GAE to develop.

What are the risks and side effects of GAE?

GAE is considered a very safe procedure with minimal risks. The most common side effects are mild and temporary, including slight soreness at the access site, minor bruising or occasional low-grade fever for 24-48 hours. Serious complications are rare, occurring in less than 1% of cases. These might include infection, blood clots or damage to the surrounding blood vessels. The risk profile is significantly lower than knee replacement surgery.

Is GAE covered by insurance?

Yes, genicular artery embolization is covered by most major insurance plans, including Medicare. The procedure has received widespread acceptance from insurance providers due to its proven effectiveness and cost-efficiency compared to knee replacement surgery. However, we always recommend contacting your insurance provider beforehand to understand your specific coverage details and any potential out-of-pocket costs. Our team can help verify your benefits and work with your insurance company to ensure coverage.

Take the First Step Toward Relief

Three Locations, One Commitment: Your Care

Lake Forest

29300 Portola Parkway, Suite B

Lake Forest, CA 92630

Mission Viejo

26921 Crown Valley Parkway, #120

Mission Viejo, CA 92691

Irvine

18102 Sky Park Circle South, Suite D

Irvine, CA 92614

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