Genicular Artery Embolization (GAE)

Are you struggling with chronic knee pain from osteoarthritis? You may worry that knee replacement surgery is your only option, but there are newer treatments that can provide relief with less discomfort, scarring and downtime. At Minimally Invasive Medical Group, we use genicular artery embolization (GAE) to reduce knee pain and help you avoid joint replacement surgery.

Book Appointment

What Is Genicular Artery Embolization?

Osteoarthritis is a frequent cause of knee pain, especially in later life. After decades of motion, natural wear and tear reduces the protective cartilage that covers your bones and cushions the joint.

Without protection, the bone ends catch and rub, creating inflammation. The inflammation causes long-term joint pain that steadily gets worse. The knee joint becomes stiffer and weaker as the condition progresses, and you may eventually lose mobility and function.

Genicular artery embolization blocks some of the blood vessels that contribute to these problems. Reducing blood flow into the joint helps decrease inflammation and pain, giving you relief from discomfort without the need to remove or replace any part of your knee.

GAE is safe and effective, lasts for years and is covered by medical insurance. You can even have the procedure after knee replacement surgery if you still experience pain.

How Does GAE Work?

During a GAE procedure, the interventional radiologist makes a small puncture in the skin to access the artery. Using X-ray imaging, they guide a thin, flexible tube (catheter) toward the genicular arteries that feed inflammation in the knee joint and release tiny particles called microspheres.

The microspheres block the passage of blood through the vessel. This causes the artery to shut down so less blood flows to the inflamed areas of the knee. Healthy circulation to the rest of the knee is not disrupted.

Start Your Journey

Benefits of Genicular Artery Embolization

Book Appointment

Knee osteoarthritis is a progressive condition that becomes increasingly painful. Knee replacement is often the suggested solution, but you may not be a good candidate for surgery, or you may simply not be interested in an invasive procedure.

GAE is an alternative option for reducing knee pain with many additional benefits:

  • Minimally invasive, outpatient procedure
  • No large incisions
  • No removal of bone
  • No general anesthesia
  • No overnight hospital stay
  • Minimal downtime
  • Targeted treatment that only affects the problematic area
  • Lower risk of complications compared to invasive surgery
  • No age, weight or health condition restrictions
  • Preserves your natural knee joint
  • No effect on candidacy for future knee replacement
  • Long-lasting pain relief that can extend for months or years
  • Covered by Medicare

How Does GAE Work?

Before recommending a treatment plan, our expert team carefully evaluates each patient’s symptoms, medical history and goals. While GAE can effectively reduce knee pain for many people with osteoarthritis, we always start with a consultation to ensure it is the best course of action for you.

GAE is a versatile treatment. Unlike knee replacement surgery, GAE has no strict age or weight limitations. It can be an excellent option for patients who have already had knee surgery but still experience pain, as well as those who want to preserve the option for knee replacement in the future.

Get Your Treatment Plan

You may be a good candidate for genicular artery embolization if you:

  • Experience chronic knee pain from osteoarthritis that affects your daily activities
  • Have not found adequate relief from conservative treatments like medications or physical therapy
  • Have tried steroid injections but found the relief 
too temporary
  • Do not wish to use medications long-term
  • Want to avoid or delay knee replacement surgery
  • Are not a good candidate for knee replacement
  • Desire a solution with minimal downtime

What to Expect During Treatment

The OCIR team provides a comfortable, well-organized experience from start to finish. The full visit typically takes a few hours, with the GAE procedure itself lasting about 60-90 minutes.

On the day of your procedure, you will arrive at our modern outpatient facility where our team will help you get settled. We will place an IV line to administer moderate sedation and any necessary medications to keep you comfortable. We will also clean the treatment area in your upper thigh and numb it with local anesthesia.

During the procedure, you will lie comfortably on your back while our interventional radiologist uses the catheter and advanced imaging technology to target the vessels causing inflammation in your knee. While you will be awake during the procedure, the sedation helps you feel relaxed, and the anesthesia ensures you feel nothing more than slight pressure. You will be always be able to communicate with your doctor and medical team.

After the procedure is complete, you will spend some time in our recovery area while the sedation wears off. Our team will come in periodically to check your vitals and the procedure site until you are deemed safe to discharge.

Genicular Artery Embolization Recovery

Most patients go home within a few hours of the procedure. You will have a small bandage at the access site in your upper thigh, but no stitches are needed. You might experience some mild soreness at this site for a day or two.

Our team will provide detailed instructions for caring for the access site and any other recovery guidelines you should follow. Many patients return to desk work within one to two days and light activities within one week. We will work with you on an appropriate timeline for returning to more strenuous activities based on your individual healing response.

You may notice some improvement in your knee pain right away. However, the full benefits of GAE develop over time, as the inflammation in your knee eases. You should feel the pain starting to lessen after two weeks and significantly after one month.

Why Choose OCIR for Your GAE Procedure

Our team brings together industry-leading expertise in interventional radiology with an unwavering commitment to patient-centered care.

Book Appointment

When you choose OCIR, you benefit from:

  • A team of highly skilled specialists who use the latest techniques and imaging technology
  • Treatment in modern, comfortable outpatient facilities
  • Same-day appointments with minimal wait times
  • Comprehensive care from evaluation through recovery
  • A dedicated staff focused on making your experience as comfortable as possible
  • Coordination with your other healthcare providers 
to ensure seamless care

Take the First Step Toward Relief

At Orange County Interventional Radiology, we specialize in innovative, nonsurgical solutions for conditions like knee osteoarthritis. If conservative treatments aren’t providing the relief you need, it’s time to consider genicular artery embolization.

FAQ'S

Got Questions? We Have Answers

How effective is GAE for knee pain?

Clinical studies show that GAE provides significant pain relief for approximately 75-85% of patients with knee osteoarthritis. Most patients experience a meaningful reduction in pain levels within four to six weeks, with continued improvement over several months. 

The procedure has shown particular success in patients with moderate to severe knee pain who haven’t responded well to conservative treatments. Many patients report being able to return to activities they had previously given up due to pain.

How long do the results from GAE last?

The pain relief from GAE can last several years for many patients. Studies tracking patients for up to five years show sustained improvement in pain and function. Unlike steroid injections that typically provide relief for 3-6 months, GAE addresses the underlying cause of inflammation, leading to longer-lasting results. Some patients may experience a gradual return of symptoms over time as osteoarthritis progresses, but the procedure can be safely repeated if needed.

Can I have GAE if I've already had knee replacement surgery?

Absolutely. GAE can be performed even after knee replacement surgery if you’re still experiencing pain. Sometimes, patients continue to have discomfort following joint replacement due to ongoing inflammation in the surrounding tissues. GAE can effectively target these areas without affecting the artificial joint components. This makes it an excellent option for managing post-surgical pain that hasn’t responded to other treatments.

How soon can I return to normal activities after GAE?

Most patients can return to desk work and light activities within one to two days. You’ll need to avoid heavy lifting or strenuous exercise for about a week to allow the access site to heal. Walking is encouraged the day after treatment to promote healthy circulation. Many patients find they can gradually return to activities like golf, gardening or hiking within two to four weeks.

Will I need physical therapy after GAE?

While physical therapy isn’t always required after GAE, many patients benefit from a structured rehabilitation program. As your pain decreases, physical therapy can help restore strength and mobility that may have been lost due to prolonged inactivity. We often recommend waiting four to six weeks after the procedure before starting to allow the full benefits of GAE to develop.

What are the risks and side effects of GAE?

GAE is considered a very safe procedure with minimal risks. The most common side effects are mild and temporary, including slight soreness at the access site, minor bruising or occasional low-grade fever for 24-48 hours. Serious complications are rare, occurring in less than 1% of cases. These might include infection, blood clots or damage to the surrounding blood vessels. The risk profile is significantly lower than knee replacement surgery.

Is GAE covered by insurance?

Yes, genicular artery embolization is covered by most major insurance plans, including Medicare. The procedure has received widespread acceptance from insurance providers due to its proven effectiveness and cost-efficiency compared to knee replacement surgery. However, we always recommend contacting your insurance provider beforehand to understand your specific coverage details and any potential out-of-pocket costs. Our team can help verify your benefits and work with your insurance company to ensure coverage.

Our Locations

Three Locations, One Commitment: Your Care

Lake Forest

29300 Portola Parkway, Suite B
Lake Forest, CA 92630
Toll Free: (800) 267-5677

Hours of Operation

Monday: 8:00 AM – 5:00 PM
Tuesday: 8:00 AM – 5:00 PM
Wednesday: 8:00 AM – 5:00 PM
Thursday: 8:00 AM – 5:00 PM
Friday: 8:00 AM – 5:00 PM
Saturday: Closed
Sunday: Closed

Mission Viejo

26921 Crown Valley Parkway, #120
Mission Viejo, CA 92691
Toll Free: (800) 267-5677

Hours of Operation

Monday: 8:00 AM – 5:00 PM
Tuesday: 8:00 AM – 5:00 PM
Wednesday: 8:00 AM – 5:00 PM
Thursday: 8:00 AM – 5:00 PM
Friday: 8:00 AM – 5:00 PM
Saturday: Closed
Sunday: Closed

Irvine

18102 Sky Park Circle South, Suite D
Irvine, CA 92614
Toll Free: (800) 267-5677

Hours of Operation

Monday: 8:00 AM – 5:00 PM
Tuesday: 8:00 AM – 5:00 PM
Wednesday: 8:00 AM – 5:00 PM
Thursday: 8:00 AM – 5:00 PM
Friday: 8:00 AM – 5:00 PM
Saturday: Closed
Sunday: Closed

Contact Us

Additional Questions?